There's the movie, the Incredible Shrinking Pants and its rather less successful spin-off, The Incredible Staying-Exactly-The-Same-Size Pants which was a disastrous movie, but the idea was bought by Marvel Comics and following some character development resurfaced as The Incredible Hulk series.
From Somewhere In Pants: I'm all out of pants Crazy Pants Puppy Pants Don't Give Up On Pants I'm Not In Pants Could It Be I'm Falling In Pants and Without Pants to name but a few...