Also introducing from Wiltshire, Mr & Mrs Isbury and their daughter, Sal.

All rise for Mr and Mrs Ham and their son Rex. (Softers) Your first one violates The Rule!

Look who's here its Mr & Mrs O'Groats and their son John

[Rosie} CanI just say that the problem with "The Rule" is that a large proportion of places *are* named for people, whether resident or saintly. Thus Peterborough - but I'd allow this, as it's all one word, whereas Mavis Enderby (Lincs) would be instantly disqualified.
Mt & Mrs Caster and their son Don Caster.

And now, let's hear it for Mr and Mrs de Janeiro and their son Rio. (Herr Bratsche) Doesn't using the already-existing personal name as part of the "answer" defy the whole purpose of the game, which is to conjure names out of thin air, as it were? There's no essential difference, in this sense, between your two examples. BTW, aren't you up rather early this morning, for a musician? :-)