No.
An A, on the other hand?

_ F _ _ _ _ _ A L
If the word contains say two L's or F's, do they have to guessed again? I'll try an R

I'm sure that's one too few "F"s, you know.

Yes, my fault. The word I had in mind has more than one F.

Hmmm - perhaps it's about what's more fun.. if we plough on till we eliminate all possible real english words then we'll certainly get a few interesting new words emerging... or we could insist we only allow letters if it doesn't prevent the word from being "real" - with a common reference perhaps like the dictionary on the crossword solver link from earlier. It seems to me that this latter is somewhat against the spirit of the idea of the game, and also more prone to getting cocked up and annoying us. Perhaps the best answer is to bumble along and resort to Mornington Dictionary when all others fail us?

By way of case in point, and cos it's amusing to my inner-schoolboy, as far as I can work out the last "real" word the first game could have yielded was "Ejacula"

Is there a "T"?